Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypoxia
ADR ID BADD_A02233
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.02      Conditions associated with abnormal gas exchange
22.02.02.003      Hypoxia
Description A disorder characterized by a decrease in the level of oxygen in the body. [CTCAE] Sub-optimal OXYGEN levels in the ambient air of living organisms. | Relatively complete absence of oxygen in one or more tissues. [MeSH]
MedDRA Code 10021143
MeSH ID D000860; D000860; D000860
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Alveolar aeration decreased | Hypoxaemia | Hypoxemia | Hypoxia | Hypoxic | Oxygen Deficiency | Deficiency, Oxygen | Deficiencies, Oxygen | Oxygen Deficiencies | Anoxia | Anoxemia
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
CCAAT/enhancer-binding protein epsilonQ6PZD9Not Available
NADH-cytochrome b5 reductase 3P00387Not Available
NADPH--cytochrome P450 reductaseP16435T95446
Sulfotransferase 1B1O43704Not Available
Sulfotransferase 1B1P52847Not Available
UDP-glucuronosyltransferase 2B15P54855Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00970Fosphenytoin0.000338%
BADD_D00971Fosphenytoin sodium--
BADD_D00972Fospropofol disodium--
BADD_D00979Furosemide0.000158%
BADD_D00981Gabapentin0.000458%
BADD_D00982Gabapentin enacarbil0.001660%
BADD_D01001Galsulfase--
BADD_D01008Gefitinib0.000799%
BADD_D01009Gemcitabine0.005328%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01015Gemtuzumab ozogamicin--
BADD_D01016Gentamicin0.000539%
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01060Heparin0.011132%
BADD_D01081Hydralazine0.000828%
BADD_D01083Hydrochlorothiazide0.000111%
BADD_D01096Hydromorphone0.000826%
BADD_D01103Hydroxychloroquine0.000158%
BADD_D01110Hydroxyurea0.000533%
BADD_D01111Hydroxyzine0.000260%
BADD_D01119Ibrutinib--
BADD_D01120Ibuprofen0.000056%
BADD_D01130Idelalisib0.001066%
BADD_D01133Ifosfamide0.000533%
BADD_D01135Iloprost0.000532%
BADD_D01136Imatinib--
BADD_D01144Immunoglobulin (human)--
BADD_D01145Immunoglobulin g (human)--
BADD_D01146Inamrinone--
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